Tumor Hypoxia and Metastasis
Context Solid tumors are characterized by areas of hypoxic tissue heterogeneously distributed inside the tumor mass.
Microphysiological System
Tumor microenvironment (TME)
The tumor microenvironment (TME) is a complex biochemical network that includes multiple factors surrounding tumor cells,
In Vitro Immune Organs-on-Chip for Drug Development
Organs-on-Chip for Drug Development A drug should pass the preclinical evaluation phase to be FDA-approved. This
Nanoscopy to improve drug screening and liver fenestrations
Introduction Drug induced liver injury (DILI)is one of the major reasons of drug attrition and it
Liver function and liver on a chip
Introduction The liver is a fundamental organ for human life. It is responsible for macromolecules (carbohydrates,
The Challenge for Development of Valuable Immuno-oncology Biomarkers
Introduction In this paper, Mehnert JM and colleagues discussed the new advances in immuno-oncology and related biomarkers
Live-cell and perfusion: weak protein-protein interactions
Introduction Weak protein-protein interactions are a common phenomenon inside cells. Besides being well known, it has a crucial
Accuracy and Precision in Measurements
Introduction: Trueness, accuracy and precision The words accuracy, trueness and precision are important differentiated terms when referring to measurements in the scientific and
Gradients generation for cell biology in microfluidics
Chemical gradients play a key role in many biological processes and regulate a number of cellular
Human cells: pH monitoring in microfluidics
Introduction The ultimate goal in microfluidics is to achieve the so-called laboratory-on-a-chip, i.e. integrate all those activities
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