Animal Testing Landscape 2025
About this white paper Animal testing has played a crucial role in medical advancements, leading to
Microphysiological System
Environmentally Controlled Microfluidic System Enabling Immune Cell Flow and Activation in an Endothelialised Skin-On-Chip
Abstract Integration of reconstructed human skin (RhS) into organ-on-chip (OoC) platforms addresses current limitations imposed by
Are spheroids recapitulating basic physiology of human organs?
Spheroids, as a good universal organ model ? Recent advances in bioengineering of cells, tissue coupled
Multiorgan Microphysiological Systems as Tools to Interrogate Interorgan Crosstalk and Complex Diseases
Introduction MPS (Multiorgan Microphysiological Systems) have evolved from tools to reduce animal experimentation and improve preclinical
Introduction to the human body
The human body: systems, organs, and main functions The human body is composed of several different
Microfluidic organ-on-chip system for multi-analyte monitoring of metabolites in 3D cell cultures
Introduction The researchers created a microfluidic organ-on-chip solution with integrated electrochemical microsensor arrays enabling compartmentalized matrix-based organoid culture
A versatile microfluidic tool for the 3D culture of HepaRG cells seeded at various stages of differentiation
Introduction Animal models and two-dimensional (2D) cell cultures frequently fail to replicate human drug metabolism and liver
Probing Insulin Sensitivity with Metabolically Competent Human Stem Cell-Derived White Adipose Tissue Microphysiological Systems
Introduction Adipose Tissue is very versatile and essential for studies related to Obesity and Diabetes, however, the high buoyancy, fragility,
Facilitating implementation of organs-on-chips by open platform technology
Introduction Many Organ-on-Chip platforms are still not robust for all cell types, are not reproducible from experiment to
Pumpless, modular, microphysiological systems enabling tunable perfusion for long-term cultivation of endothelialized lumens
Introduction The authors present a simple and modular Microphysiological system without the use of complex components consisting of
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