Congratulation to Dr. W. Kaelin, Dr. G. Semenza and Dr. P. Ratcliffe for their Nobel prize in medicine about cells adaptation mechanism to low oxygens availability. Our development of CubiX makes sense in the context of life-saving treatment such a new cancer therapy, ischemic accident recovery. We also take benefit from their reserach in our recent stomach-on-a-chip and microbiota study, in which low oxygen value adaptation is critical.